Here are the results tested on a Intel H55 board with an external 1.5TB Seagate USB 2.0 HDD.
As the patch increases the block size, it will have more impact on sequential read and write.
From CrystalDiskMark, we can clearly see that the sequential read increases from 34MB/s to 43MB/s giving a 26% increase in speed. Likewise the write performance is increased from 23MB/s to 27MB/s, a 15.58% improvement.
Here are the results before patch.
Results after patching